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Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)

The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials.

FromNational Institutes of Health
Who can applystate governments, counties, cities and townships, special districts (water, fire, parks, etc.), school districts, public colleges and universities and 9 more types
Eligibility notesRefer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.)
How muchup to $450K per award
DeadlineMon, Jul 16, 2029 (997 days left)
CategoryHealth
TypeGrant
Opportunity #PAR-28-093
Assistance listing93.279, 93.310, 93.681
PostedMon, Oct 19, 2026

Open the official posting

From the notice

The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include: 1) developing interventions to prevent substance use, misuse, or progression to substance use disorder; 2) prevention, treatment, or recovery services research, including research addressing comorbid pain and medical and mental health disorders; and 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.

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