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NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization.

FromNational Institutes of Health
Who can applysmall businesses
How muchAmount not stated
DeadlineThu, Apr 5, 2029 (895 days left)
Matching fundsYes: you must put up some of your own money or in-kind match
CategoryHealth
TypeGrant
Opportunity #PA-27-101
Assistance listing93.233, 93.242, 93.273, 93.307, 93.313, 93.350, 93.351, 93.393, 93.394, 93.395, 93.837, 93.838, 93.839, 93.840, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867
PostedThu, May 28, 2026

Open the official posting

From the notice

The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization. The Phase IIB Strategic Breakthrough provides previously funded NIH SBIR or STTR projects additional support for later-stage research and development (R&D).

We may have shortened this. The official posting is the record. We are not affiliated with the agency that published it.